We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Improved sleep quality
262 people found this helpful
After taking magnesium, I found I became much calmer, my sleep improved, and my legs stopped hurting. Magnesium is crucial for our bodies and is recommended for pregnant women. I take 2 capsules after meals or 30-40 minutes before bedtime. Since using this product, I sleep well, feel less fatigued, and manage my duties as a mother more effectively. I highly recommend it; the quality matches the price, and I appreciate the capsule size.
Read More
9
Increased energy levels
90 people found this helpful
I've taken this vitamin for a few months, and it has significantly changed my life. I've noticed enhanced strength, improved mood, and reduced fatigue, which has boosted my energy levels substantially.
Read More
9
Effective dosage
27 people found this helpful
Excellent! I suffer from restless legs syndrome and magnesium is essential for me. I regularly order various types, considering both dosage and recommendations. This magnesium works well; I sleep soundly without experiencing cramps or nausea. It suits me perfectly.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 57 Reviews
8
All Reviews
Positive Reviews
Negative Reviews
9
Improved sleep quality
262 people found this helpful
After taking magnesium, I found I became much calmer, my sleep improved, and my legs stopped hurting. Magnesium is crucial for our bodies and is recommended for pregnant women. I take 2 capsules after meals or 30-40 minutes before bedtime. Since using this product, I sleep well, feel less fatigued, and manage my duties as a mother more effectively. I highly recommend it; the quality matches the price, and I appreciate the capsule size.
Read More
9
Increased energy levels
90 people found this helpful
I've taken this vitamin for a few months, and it has significantly changed my life. I've noticed enhanced strength, improved mood, and reduced fatigue, which has boosted my energy levels substantially.
Read More
9
Effective dosage
27 people found this helpful
Excellent! I suffer from restless legs syndrome and magnesium is essential for me. I regularly order various types, considering both dosage and recommendations. This magnesium works well; I sleep soundly without experiencing cramps or nausea. It suits me perfectly.
Read More
9
Replenishes deficiency
14 people found this helpful
CHELATED FORM OF MAGNESIUM! Most people are magnesium deficient, which can cause chronic fatigue syndrome and other health issues. This supplement helps replenish magnesium levels effectively, improving sleep quality by regulating cortisol levels.
Read More
9
Regulated bowel movements
11 people found this helpful
The supplement helped my wife, who has Irritable Bowel Syndrome and chronic fatigue syndrome. After years of struggling with constipation, this has significantly improved her bowel movements to twice daily. The magnesium complex is high quality and easy to ingest.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, many individuals taking magnesium supplements for Chronic Fatigue Syndrome (CFS) report experiencing noticeable improvements within a couple of weeks. For instance, one user mentioned feeling significant relief from fatigue and anxiety after two weeks of consistent use Read Review. Another user noted that they felt more energetic and saw a reduction in muscle fatigue after taking the supplement daily Read Review.
Moreover, some users imply that the benefits can become more pronounced with continued use over time. One reviewer experienced mood improvements and increased vitality after several weeks of supplementation Read Review. Though individual results may vary, it seems that a majority of users expect to notice benefits within a relatively short time frame, typically within two to four weeks of consistent use.
Magnesium supplements appear to have some potential in alleviating symptoms of Chronic Fatigue Syndrome (CFS), though scientific research remains inconclusive. Several studies have indicated that magnesium deficiency may be widespread among individuals suffering from unexplained fatigue, which could link it to CFS [2]. In a randomized, double-blind trial, magnesium sulfate treatment resulted in significant improvements in energy levels, emotional wellbeing, and pain relief for a majority of CFS patients, suggesting it may positively impact their overall quality of life [5]. However, while these findings are promising, researchers emphasize the need for further rigorous studies to substantiate these effects and provide a clearer understanding of magnesium's potential role as a treatment for CFS [1].
On the other hand, some studies have documented mixed results, indicating that while magnesium might help some patients, it is not a one-size-fits-all remedy [4]. Other treatment methods are currently debated, and magnesium supplementation did not result in a significant boost in antioxidant activity or alleviate fatigue in some research contexts [2]. Therefore, while there is some supportive evidence regarding magnesium's effects on CFS symptoms, the current level of scientific backing suggests more research is necessary to draw definitive conclusions.
Users of this magnesium supplement have reported a variety of improvements in their symptoms, particularly regarding chronic fatigue syndrome, muscle tension, and sleep quality. For instance, one reviewer noted significant relief from chronic fatigue and improved sleep patterns after using the supplement regularly, stating they could manage their responsibilities more effectively Read Review. Another user highlighted enhanced mood and energy levels, mentioning a substantial boost in their overall vitality Read Review.
Additionally, those suffering from specific conditions, such as restless legs syndrome, reported marked improvements in symptoms, experiencing better sleep devoid of cramps and anxiety Read Review. The supplement appears to play a crucial role in not only alleviating physical symptoms, such as muscle spasms and fatigue, but also in enhancing mental well-being Read Review. While individual results may vary, the consensus among users is that consistent use over a short period can lead to notable benefits for both physical and mental health.
Users have reported positive experiences when combining this magnesium supplement with other supplements to manage Chronic Fatigue Syndrome (CFS). One reviewer shared that they've found relief by alternating different types of magnesium for optimal absorption, which has transformed their struggle with CFS into a more tranquil existence Read Review. Another user mentioned that they are exploring additional magnesium products alongside their current supplement to enhance their health further. They noted significant results after a couple of weeks of use, which indicates that integrating this supplement with others may support a more comprehensive approach to handling fatigue Read Review.
Moreover, some users have indicated that their overall symptoms improved significantly without the presence of discomfort often associated with other magnesium forms Read Review. This supplement appears to work synergistically with various supplements to enhance vital nutrient levels, particularly for those struggling with CFS. While individual results may vary, many users advocate for a multi-faceted approach in managing their symptoms, frequently emphasizing the importance of adjusting dosages and incorporating other health products to maximize benefits Read Review.
Users report varying dosages of magnesium for alleviating symptoms of Chronic Fatigue Syndrome, often emphasizing personal experimentation to find the right amount. Many users recommend starting with one or two capsules daily, with some asserting that taking magnesium in the evening enhances sleep quality and reduces fatigue. For instance, a user mentioned experiencing significant improvements with two capsules taken before bed, which helped ease fatigue and improve overall energy levels Read Review. Another user found that one tablet was sufficient for their needs Read Review, while others suggested that adjustments are necessary based on individual responses Read Review.
The general consensus among reviewers is that magnesium plays a crucial role in managing symptoms related to Chronic Fatigue Syndrome, with many noticing enhanced mood and energy levels with regular supplementation. One user indicated that alternating different forms of magnesium might optimize absorption, further supporting the idea that finding a personalized dosage is key Read Review. Overall, while one to two capsules daily seems to be a common approach, individual variations should be considered for optimal results.
9
Nerve exhaustion relief
32 people found this helpful
Doctors recommend magnesium for muscle weakness and nervous exhaustion. After two weeks of taking it, I've noticed a calmness I didn't expect. I feel less irritable, showing significant improvement in managing my chronic fatigue syndrome. Thank you, iHerb!
9
Normalised heartbeat
4 people found this helpful
Since using this magnesium, my chronic fatigue syndrome symptoms have improved; my heartbeat is regular and my muscle fatigue has eased significantly. I recommend taking it before bed.
9
Increased vitality
19 people found this helpful
Magnesium energises me; my days are filled with vitality, activity, and enthusiasm. I maintain a clean home without feeling lazy or lethargic, and I experience no fatigue. I will always purchase from this reliable brand.
9
Improved sleep quality
262 people found this helpful
After taking magnesium, I found I became much calmer, my sleep improved, and my legs stopped hurting. Magnesium is crucial for our bodies and is recommended for pregnant women. I take 2 capsules after meals or 30-40 minutes before bedtime. Since using this product, I sleep well, feel less fatigued, and manage my duties as a mother more effectively. I highly recommend it; the quality matches the price, and I appreciate the capsule size.
9
Increased energy levels
90 people found this helpful
I've taken this vitamin for a few months, and it has significantly changed my life. I've noticed enhanced strength, improved mood, and reduced fatigue, which has boosted my energy levels substantially.
9
Effective dosage
27 people found this helpful
Excellent! I suffer from restless legs syndrome and magnesium is essential for me. I regularly order various types, considering both dosage and recommendations. This magnesium works well; I sleep soundly without experiencing cramps or nausea. It suits me perfectly.
7.5
Enhanced mood
168 people found this helpful
This magnesium supplement replenishes deficiency and improves mood while relieving irritability and fatigue. It also eliminates muscle spasms, and the packaging lasts a long time. I highly recommend ordering from the Iherb website.
9
Improved tension relief
8 people found this helpful
This magnesium supplement significantly reduces muscle tension and anxiety for me. I've noticed remarkable benefits, including better sleep and less fatigue. Magnesium is vital, as it's hard to ingest enough from food alone. I alternate different magnesium forms for optimal absorption and feel confident in its positive impact on my health, transforming my life from chronic fatigue syndrome into a calmer existence.
7.5
Relieved constipation
8 people found this helpful
I purchased these magnesium capsules to alleviate my lifelong chronic constipation, and they truly work. After a couple of weeks taking two capsules daily, I experienced loose stools for the first time. While I'm unsure of their effectiveness for magnesium deficiency due to the inclusion of less well-absorbed magnesium forms, I'm pleased with the results. I'm exploring additional magnesium products alongside these.
7.5
Alleviated constipation
8 people found this helpful
I find this product effective for chronic fatigue syndrome, helping my constipation significantly. Unlike other magnesium forms that made me feel unwell, this one suits me perfectly and enhances my sleep quality.
7.5
Reduced appetite control
4 people found this helpful
Magnesium has improved my sleep quality and helped alleviate chronic fatigue syndrome symptoms. After struggling with insomnia, I find that it reduces headaches and improves my overall appetite control.
9
Nerve exhaustion relief
Doctors advise magnesium for muscle weakness and chronic fatigue syndrome. After taking it for two weeks following severe nerve exhaustion, I’m thrilled with the results. My anxiety has decreased significantly.
6
Relieves constipation
I was hoping to alleviate my chronic constipation. After taking one tablet on an empty stomach before bed, I had a natural bowel movement the next morning. When one tablet didn’t suffice, I took two and felt refreshed the following day. I will continue to adjust my dosage.
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.